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Modelling and Simulation of Genetic Regulatory System

The genome of an organism plays a central rolein the control of cellular processes, such asthe response of a cell to environmental signals, the differentiation of cells and groups of cells in theunfolding of developmental programs, and the replication of the DNA preceding cell division. Proteinssynthesized from genes may function as transcription factors binding to regulatory sites of other genes,as enzymes catalyzing metabolic reactions, or as components of signal transduction pathways. With fewexceptions, all cells in an organism contain the same genetic material. This implies that, in order tounderstand how genes are implicated in the control of intracellular and intercellular processes, the scopeshould be broadened from sequences of nucleotides coding for proteins to regulatory systems determiningwhich genes are expressed, when and where in the organism, and to which

Author : Hidde De Jong

Updated on February 27, 2019

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